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7,8-dihydrofolate

Properties

Image

Occurences in reactions

MNX_ID

MNXM281

	#reac
in my sandbox	0
in MNXref (generic)	25
in models (compartimentalized)	25

formula

C₁₉H₁₉N₇O₆

charge

-2

mass

441.404

reference

chebi:57451

InChIKey

OZRNSSUDZOLUSN-LBPRGKRZSA-L

InChI

InChI=1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/p-2/t12-/m0/s1

SMILES

[cH:1]1[cH:3][c:10]([NH:21][CH2:7][C:11]2=[N:23][c:14]3[c:15]([nH:25][c:19](=[NH:20])[n:26][c:17]3[OH:30])[NH:22][CH2:8]2)[cH:4][cH:2][c:9]1[C:16]([NH:24][C@@H:12]([CH2:5][CH2:6][C:13](=[O:27])[OH:28])[C:18](=[O:31])[OH:32])=[O:29]

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Similar chemical compounds in external resources
Identifier	Description
CHEBI:57451 chebi:57451	7,8-dihydrofolate N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamate dihydrofolate dianion dihydrofolate(2-)
hmdb:HMDB0246644	2-(4-(((2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid 2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid 2-[(4-{[(4-hydroxy-2-imino-1,2,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioate dihydrofolate
CHEBI:182629 chebi:182629	2-(4-(((2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid 2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
bigg.metabolite:dhf biggM:dhf	7,8-Dihydrofolate
vmhM:dhf vmhmetabolite:dhf	7,8-Dihydrofolate (2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
metacyc.compound:DIHYDROFOLATE metacycM:DIHYDROFOLATE	7,8-dihydrofolate monoglutamate 7,8-dihydrofolate 7,8-dihydropteroyl monoglutamate 7,8-dihydropteroylglutamate 7,8-pteroylglutamate 7,8-pteroylglutamic acid H2PteGlu H2PteGlu1 dihydrofolate
hmdb:HMDB0304237	7,8-dihydrofolate 2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioate 2-[(4-{[(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioate 4-Carboxy-4-[(4-{[(2-imino-4-oxido-1,2,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]butanoic acid 7,8-Dihydrofolic acid
seed.compound:cpd00330 seedM:cpd00330	Dihydrofolate 7,8-Dihydrofolate 7,8-Dihydrofolic acid 7,8-Dihydropteroylglutamate 7,8-dihydrofolate 7,8-dihydrofolate monoglutamate 7,8-dihydropteroyl monoglutamate 7,8-dihydropteroylglutamate 7-8-Dihydrofolate DHF Dihydrofolic acid FH2 H2PteGlu H2PteGlu1 dhf dihydrofolate
kegg.compound:C00415 keggC:C00415	Dihydrofolate 7,8-Dihydrofolate 7,8-Dihydrofolic acid 7,8-Dihydropteroylglutamate Dihydrofolic acid
sabiork.compound:1336 sabiorkM:1336	Dihydrofolate 7,8-Dihydrofolate 7,8-Dihydrofolic acid Dihydrofolic acid H2PteGlu1
hmdb:HMDB0001056	Dihydrofolic acid (2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid 7,8-Dihydro-L-folic acid 7,8-Dihydrofolate 7,8-Dihydrofolic acid 7,8-Dihydropteroylglutamate 7,8-Dihydropteroylglutamic acid Dihydrofolate Dihydrofolate, (D)-isomer H2PteGlu H2PteGlu1 L-N-[p-[[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-glutamic acid N-(4-(((2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid N-(7,8-Dihydropteroyl)-L-glutamate N-(7,8-Dihydropteroyl)-L-glutamic acid N-[4-[[(2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid Vitamin b9 dihydrofolic acid
reactome:R-ALL-73604 reactomeM:R-ALL-73604 CHEBI:15633 chebi:15633	dihydrofolic acid 7,8-Dihydrofolate 7,8-Dihydrofolic acid 7,8-Dihydropteroylglutamate Dihydrofolate Dihydrofolic acid N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid N-(7,8-dihydropteroyl)-L-glutamic acid
hmdb:HMDB01056 chebi:12245 chebi:14150 chebi:20768 chebi:42000 chebi:4564 biggM:M_dhf keggC:M_C00415 seedM:M_cpd00330	secondary/obsolete/fantasy identifier